VISDB Viral Integration Site DataBase

VIS ID

TVIS10008680

Fusion event

HBV-KIAA0319L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1954

Orient

+

Integrated sequence

TGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGT| |TTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCA

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

35970105/35504504 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-423-3p ; hsa-mir-432-5p ; hsa-mir-218-5p ; hsa-mir-5689 ; hsa-mir-571 ; hsa-mir-219a-1-3p ; hsa-mir-129-5p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-431-5p ; hsa-mir-4294 ; hsa-mir-3194-3p ; hsa-mir-924

Nearest miRNA

hsa-mir-12136/Upstream/834810; hsa-mir-101-1/Downstream/1657059;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/235250, chr1-CpG: 95/Downstream/52575

Upstream sequence

ccagaatggtctcgatctcctgaccttgtgatccgcccgccttggcctcccaaagtgctgggattacaggcataagccatcacacccagccaattttctt

Downstream sequence

aacattttatctagtttaagaatacagtatataatgcatatgacatacataatatgtgttaatcgactgtttatcttattggtaaggcttccagtcaaca