VISDB Viral Integration Site DataBase

VIS ID

TVIS10008685

Fusion event

HBV-ZFYVE9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1032

Orient

+

Integrated sequence

AAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTA| |CACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACA

Chromosome

chr1

Cytoband

p32.3

Reference genome

Start

End

52796384/52330712 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-222-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-580-5p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-1225-5p ; hsa-mir-1229-5p ; hsa-mir-4295 ; hsa-mir-4328 ; hsa-mir-3666 ; hsa-mir-5002-3p ; hsa-mir-141-5p ; hsa-mir-145-5p ; hsa-mir-5195-3p ; hsa-mir-4643 ; hsa-mir-526b-5p ; hsa-mir-591 ; hsa-mir-6758-5p ; hsa-mir-6856-5p ; hsa-mir-4684-3p ; hsa-mir-503-3p ; hsa-mir-367-5p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-4755-3p ; hsa-mir-4753-5p ; hsa-mir-6768-3p

Nearest miRNA

hsa-mir-12136/Upstream/494310; hsa-mir-101-1/Downstream/1723367;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/187880, chr1-CpG: 72/Downstream/35019

Upstream sequence

tataattagtgataatgagcagtgaggacctccagtggtcactttcatcaccatcttggttttggtgggttttggctagcttctttacagcattctgttt

Downstream sequence

ttatcagtggggtctttgtgacctgtatcttgtgctttcctcctatcctaagaatgcccaacctcctgggatgcagcccagcaggtttcagcctcatttt