VISDB Viral Integration Site DataBase

VIS ID

TVIS10008686

Fusion event

HBV-TUT4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

288

Orient

+

Integrated sequence

CCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGA| |ACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGC

Chromosome

chr1

Cytoband

p32.3

Reference genome

Start

End

52903084/52437412 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-196a-5p ; hsa-let-7b-5p ; hsa-mir-26a-5p ; hsa-mir-4791 ; hsa-mir-3201 ; hsa-mir-203a-3p ; hsa-mir-216b-5p

Nearest miRNA

hsa-mir-12136/Upstream/601010; hsa-mir-101-1/Downstream/1616667;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/32779, chr1-CpG: 115/Downstream/115174

Upstream sequence

agtgatggaaactggaagttcgttctgtctcaaaagttccaagtttttaTTTTAGGCCAGACTTGATGACAAAAGAAAGAGATCTTCCTGACCTACTACA

Downstream sequence

GTATACAGAACCTGGGAGACTATAATTCGTAGATATATTTTGAGGGAGTATAGAAGATGTACATTCCCCAAGATCTATAAATATAGCTCACAGCATGTTA