HABP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008695
Fusion event
HBV-HABP2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1979
Orient
+
Integrated sequence
TGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTC| |AGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATT
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
115334530/113574771 (Hg38)
End
115334530/113574771 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
HABP2
Nearest miRNA
hsa-mir-107/Upstream/940517; hsa-mir-202/Downstream/203222;
Nearest TSS
ENST00000439456/Upstream/7287; ENST00000468790/Downstream/89275;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/408779, chr10-CpG: 101/Downstream/104477
Upstream sequence
agcaagttaatgcagcattgtccaggtttcctgaTGCTGTGAATAGCAGCTGTATTCAAAATCACTCCCATAGCTTAGATTACAGGTCAGACCCTAAGGA
Downstream sequence
TGCAGGAAGTCCATGTCAGCCTTGAGTACCAGACTGTAGCATGTACACATTCAGCTTTGGGACTTTCCTTCCCTCATGCCTTTGCCAGAACTTTTCCTTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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