VISDB Viral Integration Site DataBase

VIS ID

TVIS10008701

Fusion event

HBV-SVIL integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

82

Orient

-

Integrated sequence

AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAA| |CAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCT

Chromosome

chr10

Cytoband

p11.23

Reference genome

Start

End

29886193/29597264 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-let-7e-5p

Nearest miRNA

hsa-mir-1265/Upstream/52167; hsa-mir-107/Downstream/5000;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/187149, chr10-CpG: 234/Downstream/137879

Upstream sequence

atacgcgttaagagacaaaatggcgaagtatgatattgtgggcatgtgcataactccttaaacgggctgcactgctcacttccaaaggggaaagagggca

Downstream sequence

ctgagcatgcagaaagcccgccctgagggaagaatcatgggagagagggcagcctataaagtcccaggatcaagggtaaatgcctcctttttttttctct