VISDB Viral Integration Site DataBase

VIS ID

TVIS10008702

Fusion event

HBV-ZNF248 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1810

Orient

-

Integrated sequence

CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT

Chromosome

chr10

Cytoband

p11.21

Reference genome

Start

End

38077399/37788471 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1226-3p ; hsa-mir-29b-2-5p ; hsa-mir-4311 ; hsa-mir-515-5p ; hsa-mir-519d-5p ; hsa-mir-519e-5p ; hsa-mir-5695 ; hsa-mir-629-3p ; hsa-mir-634

Nearest miRNA

hsa-mir-1265/Upstream/2147219; hsa-mir-107/Downstream/5209092;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/7453, chr10-CpG: 68/Downstream/69103

Upstream sequence

gcactttgggaggctgaggcaggtggatcacctgaggtcaggagttcaagactaacctggtcaacatggtgaaaccccatctctaccaagaatacaaaaa

Downstream sequence

ttacccaggcttggtggcatgtgcctgtaatcctagctactcaggagactgaggcaggagaatcacttaagcctgggaggtggaggttgcagtgagccat