VISDB Viral Integration Site DataBase

VIS ID

TVIS10008703

Fusion event

HBV-ZNF248 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1866

Orient

+

Integrated sequence

TCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTT| |CAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTG

Chromosome

chr10

Cytoband

p11.21

Reference genome

Start

End

38077400/37788472 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1226-3p ; hsa-mir-29b-2-5p ; hsa-mir-4311 ; hsa-mir-515-5p ; hsa-mir-519d-5p ; hsa-mir-519e-5p ; hsa-mir-5695 ; hsa-mir-629-3p ; hsa-mir-634

Nearest miRNA

hsa-mir-1265/Upstream/2147220; hsa-mir-107/Downstream/5209091;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/7454, chr10-CpG: 68/Downstream/69102

Upstream sequence

cactttgggaggctgaggcaggtggatcacctgaggtcaggagttcaagactaacctggtcaacatggtgaaaccccatctctaccaagaatacaaaaat

Downstream sequence

tacccaggcttggtggcatgtgcctgtaatcctagctactcaggagactgaggcaggagaatcacttaagcctgggaggtggaggttgcagtgagccatg