VISDB Viral Integration Site DataBase

VIS ID

TVIS10008715

Fusion event

HBV-ANK3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1899

Orient

+

Integrated sequence

TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG| |GGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATA

Chromosome

chr10

Cytoband

q21.2

Reference genome

Start

End

62243377/60483619 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-8088 ; hsa-mir-598-5p ; hsa-mir-216b-3p ; hsa-mir-8485 ; hsa-mir-603 ; hsa-mir-503-5p ; hsa-mir-34a-5p

Nearest miRNA

hsa-mir-1265/Upstream/3179060; hsa-mir-107/Downstream/2889338;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/576583, chr10-CpG: 60/Downstream/249408

Upstream sequence

ATAAGATGACAAAGACCTTTGATCCAATGGGTTCTGTTCAGCTCTTTTTGTATGCTTAGGAAAGTTAACTGATTTTTTTTCTCTTTGATTTTATATCAAT

Downstream sequence

GTGTAATAGCAATTTTAAAATGACACAGAGCATATTTTGTTAGGCTTTCGCTTTTAATGACAATGATTTCGAAGCCTGAATGTTTTCTCGACCTCCCCCT