Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008728
Fusion event
HBV-SPON1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
965
Orient
-
Integrated sequence
CTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATT| |AACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGT
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
Start
End
14281286/14259740 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-210/Upstream/2095973; hsa-let-7a-2/Downstream/1709793;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/122, chr11-CpG: 110/Downstream/98522
Upstream sequence
GATGGCTCCATGTGCAAAGCCGAGACATCACAGGCAGAGAAGTGCATGATGCCAGAGTGCCGTGAGTGAGAGCGGGGGTGGACTTGGAGGAGGCCACTGG
Downstream sequence
GGACAGGCGTGGAGGGCCATGGCATCCACTATTACCACCATAAAGGTCGGAGGCTGAGCAGAGGAAAGCATGGCCCATGGTCCTTGCTGGGCACTGCTGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.