Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008730
Fusion event
HBV-MOB2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1848
Orient
+
Integrated sequence
AGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCT| |TGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTAC
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
Start
End
1709749/1688519 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-210/Upstream/431849; hsa-let-7a-2/Downstream/170945;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/35525, chr11-CpG: 21/Downstream/5598
Upstream sequence
TGAGCCATGGCCTCCGGGGCACCGGAGCCACAGAGCCACCACGCTTTGCTTTTGTTTCTCACTCCCCTACTCTCCCCACATAGGCACCGACGCTTTCCCT
Downstream sequence
GACAGCATCATCATCACCCAACTAGGGCAGCTGACCCGCGTCTTCCTCACGACGTGGAATGGTTTGAGTCAAGGGTTTTCATGGCCATGAGCCACGTGGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.