TMEM132D _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008746
Fusion event
HBV-TMEM132D integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2632
Orient
+
Integrated sequence
AACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAA| |TTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACT
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
129937803/129453258 (Hg38)
End
129937803/129453258 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
TMEM132D
Nearest miRNA
hsa-let-7i/Upstream/1159080; hsa-mir-6763/Downstream/3128739;
Nearest TSS
ENST00000382841/Upstream/244657; ENST00000536512/Downstream/69505;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/149643, chr12-CpG: 23/Downstream/246738
Upstream sequence
cagtctgaaaccatcacccacctctctgcagtccacggaaaaattgtcttccaggaaaccagtccctggtgccaaaaagattggggaccgctgTTTTAGA
Downstream sequence
TGATCTAAGAAGGCGTGCCTACTAAACGAAGCCCATATCTGCTGGCTTTTGCAGCATGGGCTACTGGCTTTTGCGCAAGGTGTCTCTTTGCCTGGAATTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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