Basic Information
VIS ID
TVIS10008762
Fusion event
HBV-chr13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2566
Orient
+
Integrated sequence
TCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAA| |GACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTA
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
101338821/100686567 (Hg38)
End
101338821/100686567 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA13D
Nearest miRNA
hsa-mir-1297/Upstream/1043418; hsa-mir-1267/Downstream/1281075;
Nearest TSS
ENST00000623511/Upstream/11474; ENST00000457843/Downstream/21758;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/11098, chr13-CpG: 117/Downstream/729198
Nearby gene
TMTC4(-11718) ; NALCN-AS1(+21758) ;
Upstream sequence
ctcctgccccatccatgtaggatatgcctgcttccccttcaccttctgccatgattgtaagtttcctgaggcctccccagccatgtttcctatacagcct
Downstream sequence
gtggaactgtgagccaattaaacctcttttctttgtaaattacccagtctcaggtaattctttatagcaatgcgagaacagactaacacaccatccttgg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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