VISDB Viral Integration Site DataBase

VIS ID

TVIS10008763

Fusion event

HBV-COG6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1737

Orient

-

Integrated sequence

TATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGA| |GGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCC

Chromosome

chr13

Cytoband

q14.11

Reference genome

Start

End

40295976/39721839 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-875-5p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-4777-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-3613-5p ; hsa-mir-18b-3p ; hsa-mir-4328 ; hsa-mir-4781-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-6873-3p ; hsa-mir-4768-5p ; hsa-mir-627-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-5003-3p ; hsa-mir-34b-3p ; hsa-mir-551b-5p

Nearest miRNA

hsa-mir-2276/Upstream/57704; hsa-mir-1267/Downstream/1005977;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/65795, chr13-CpG: 30/Downstream/450393

Upstream sequence

TTTACTACCAATAACCTATTATTTTTTTCCCACTCTTATATAGCTTCTTCCagtgtttcaagcaagaagtccaggctagtcagattctcttgtttttagt

Downstream sequence

aatctagtcccttcatctggtaacttacagggattttccattgagtttatatgttttcccaggatatttttggtatgtctctttttaaaaattatttgca