Basic Information
VIS ID
TVIS10008767
Fusion event
HBV-chr13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1762
Orient
-
Integrated sequence
GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA| |AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTAC
Host Sequence
Chromosome
chr13
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
90385285/89733031 (Hg38)
End
90385285/89733031 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/2114291; hsa-mir-1267/Downstream/498151;
Nearest TSS
ENST00000623511/Upstream/179227; ENST00000426840/Downstream/386688;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/369510, chr13-CpG: 49/Downstream/1441964
Nearby gene
LINC00353(-168618) ; LINC00559(+327216) ;
Upstream sequence
aagtctttatttctccttcagttttgaagaataatttcataaagtactgaaatctagattggtggatttctcttgttgttgttgctgttgttgttgttct
Downstream sequence
ctgtttctcaatactttaaacattccacttcactgttatctttcttgtaatgtttttgtgtttaatttttatcgttacttctctataggtatttttttct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate