VISDB Viral Integration Site DataBase

VIS ID

TVIS10008770

Fusion event

HBV-NPAS3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1805

Orient

-

Integrated sequence

TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG

Chromosome

chr14

Cytoband

q13.1

Reference genome

Start

End

33894850/33425644 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-17-5p ; hsa-mir-3679-3p ; hsa-mir-4446-5p ; hsa-mir-361-3p ; hsa-mir-153-5p ; hsa-mir-589-3p ; hsa-mir-548as-3p ; hsa-mir-143-5p ; hsa-mir-2681-5p ; hsa-mir-3944-5p ; hsa-mir-8066

Nearest miRNA

hsa-mir-208a/Upstream/2410902; hsa-mir-1185-1/Downstream/3526665;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/485615, chr14-CpG: 152/Downstream/374096

Upstream sequence

tttttttttttagcatgttggctttgtgttcatgtgcttgacatgtaatagacactagcaagcttcttcagttccacatgacttcatttaaagcaaaaac

Downstream sequence

aaggaatgtgatttttgtgctctgtccttttatacgggaacaaaatgtgtccccagattttcctcattcctactctttcagacttgtttttgtatcgtct