VISDB Viral Integration Site DataBase

VIS ID

TVIS10008772

Fusion event

HBV-MAPK1IP1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2962

Orient

+

Integrated sequence

TTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAA| |GGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAG

Chromosome

chr14

Cytoband

q22.3

Reference genome

Start

End

55521430/55054712 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-374b-5p ; hsa-mir-193b-3p ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-mir-181a-5p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-1911-5p ; hsa-mir-4429 ; hsa-mir-4726-3p ; hsa-mir-4999-5p ; hsa-mir-490-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6874-5p ; hsa-mir-3650 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-4327 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-3192-5p ; hsa-mir-7851-3p ; hsa-mir-607 ; hsa-mir-4693-3p ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-298 ; hsa-mir-4649-3p ; hsa-mir-1282 ; hsa-mir-5707 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1827 ; hsa-mir-3937 ; hsa-mir-3942-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-485-5p ; hsa-mir-6884-5p

Nearest miRNA

hsa-mir-208a/Upstream/176519; hsa-mir-1185-1/Downstream/4592250;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/2473, chr14-CpG: 114/Downstream/74267

Upstream sequence

ACAGATGGAAAATGGTCTCTTATTGAGAAGTTTTTTGTCAAAAGATAACCGTCAAAAGGATTCATGTCCGGGTTTCATCACTGTGTAGTCCCATACTGTT

Downstream sequence

TATCACTCCATCACAATTTGAAGGCTGTCTGAAATATCCATGAACTCCACTGGTAATTCATGGAGTTCAACTCTCTTAACCACCCTCCTCCCTGACCCAT