VISDB Viral Integration Site DataBase

VIS ID

TVIS10008773

Fusion event

HBV-MAPK1IP1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1801

Orient

-

Integrated sequence

GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG

Chromosome

chr14

Cytoband

q22.3

Reference genome

Start

End

55521433/55054715 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-374b-5p ; hsa-mir-193b-3p ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-mir-181a-5p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-1911-5p ; hsa-mir-4429 ; hsa-mir-4726-3p ; hsa-mir-4999-5p ; hsa-mir-490-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6874-5p ; hsa-mir-3650 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-4327 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-3192-5p ; hsa-mir-7851-3p ; hsa-mir-607 ; hsa-mir-4693-3p ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-298 ; hsa-mir-4649-3p ; hsa-mir-1282 ; hsa-mir-5707 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1827 ; hsa-mir-3937 ; hsa-mir-3942-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-485-5p ; hsa-mir-6884-5p

Nearest miRNA

hsa-mir-208a/Upstream/176522; hsa-mir-1185-1/Downstream/4592247;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/2476, chr14-CpG: 114/Downstream/74264

Upstream sequence

GATGGAAAATGGTCTCTTATTGAGAAGTTTTTTGTCAAAAGATAACCGTCAAAAGGATTCATGTCCGGGTTTCATCACTGTGTAGTCCCATACTGTTTAT

Downstream sequence

CACTCCATCACAATTTGAAGGCTGTCTGAAATATCCATGAACTCCACTGGTAATTCATGGAGTTCAACTCTCTTAACCACCCTCCTCCCTGACCCATGAT