BTBD7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008777
Fusion event
HBV-BTBD7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1820
Orient
+
Integrated sequence
TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
End
93718618/93252272 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1260a/Upstream/15985982; hsa-mir-1185-1/Downstream/695954;
Upstream sequence
ggtggcgggtgcctatcatcccagctactcaggaggctgaggcacgagaactgcttgaactcgggaggagaaggttgtagtaagctgagatctcactgcg
Downstream sequence
gcactccagcctggatgacaagagtgaaactccgtcttaaaaaaaaaaaaaaGATTGATAATCAATTCAAGAGACTTAGAAATAAACCAAATTTTCTTTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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