VISDB Viral Integration Site DataBase

VIS ID

TVIS10008782

Fusion event

HBV-ZNF106 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2564

Orient

+

Integrated sequence

ACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACC| |AAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGT

Chromosome

chr15

Cytoband

q15.1

Reference genome

Start

End

42740773/42448575 (Hg38)

Orient

-

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-1237-3p ; hsa-mir-345-5p ; hsa-mir-28-5p ; hsa-let-7b-5p ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-3190-3p ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-605-3p ; hsa-mir-5003-5p ; hsa-mir-4289 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-374a-3p ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4795-5p ; hsa-mir-4635 ; hsa-mir-5582-3p ; hsa-mir-5698 ; hsa-mir-6879-3p ; hsa-mir-4294 ; hsa-mir-6499-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-1304-3p ; hsa-mir-5693 ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-3664-5p ; hsa-mir-1911-3p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-4468 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-1207-3p ; hsa-mir-646 ; hsa-mir-122-5p ; hsa-mir-143-5p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-24-3p ; hsa-mir-3129-5p ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-4430 ; hsa-mir-4772-3p ; hsa-mir-504-3p ; hsa-mir-6890-3p ; hsa-mir-8057 ; hsa-mir-891b ; hsa-mir-4769-3p ; hsa-mir-6817-5p

Nearest miRNA

hsa-mir-1233-1/Upstream/248909; hsa-mir-10393/Downstream/1345084;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/174369, chr15-CpG: 25/Downstream/42186

Upstream sequence

GCTCATTTTCTTTGCCTGTACCTTCCTCACTGAAGAAGCTATACACAGAAGGAGCTCTGTCCATGATCACGCTGCTCTCAGAAAGGCTTCGCTTTCTTGC

Downstream sequence

CAAGCCAGGGGACGAGGAAATGGAAACACCTTCCCACTGGAATCCTTCTAGACTGGACAGATCAGGTTCCCCATCCAAATCTAAGGCTTCTTGTTCATTT