Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008797
Fusion event
HBV-CTU2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1263
Orient
-
Integrated sequence
CGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGC| |CGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATA
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
Start
End
88780497/88714089 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-11401/Upstream/245058; hsa-mir-4722/Downstream/2189;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/7302, chr16-CpG: 31/Downstream/1654
Upstream sequence
TTCTCTGGCTGCCTTGAGCAGTCGCAGCAAAGCCAGACCCATGTGGGCCAGCAGCGTGGAACCCACGGCACCTGTCCTGGGGACTCTGCCCCAGCCTGGG
Downstream sequence
GCTGGCCTCTGGGCTTTCCCATAGCCTCCAATCTGATTGTCCCTAGGCCCCTGAAAAGGCCAGCATCCACCGGCTGATGGAGGCCTTCATCCTCAGGCTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.