Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008805
Fusion event
HBV-SEBOX integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1940
Orient
+
Integrated sequence
TCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGT| |GGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAG
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
Start
End
26693137/28366116 (Hg38)
Orient
-
Location type
upstream
Target gene
Nearest miRNA
hsa-mir-1180/Upstream/5382; hsa-mir-10226/Downstream/495253;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/8264, chr17-CpG: 116/Downstream/5222
Upstream sequence
gtggcgtgatcttggctcactgcaacctccacctcccgagttcaagcaactccacctcctgcctcttcctccggagtagctggggttacaggcgcctgcc
Downstream sequence
accacacccggctaattttttgtatttttagtagagacggggtttcaccatgttggccaggctggtctcgaactcctaacctcatgatccacgggccttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.