VISDB Viral Integration Site DataBase

VIS ID

TVIS10008811

Fusion event

HBV-BCAS3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2461

Orient

+

Integrated sequence

AGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCT| |TGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTAC

Chromosome

chr17

Cytoband

q23.2

Reference genome

Start

End

59446173/61368812 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1278 ; hsa-mir-1285-3p ; hsa-mir-2861 ; hsa-mir-3187-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-3664-5p ; hsa-mir-3667-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-4714-5p ; hsa-mir-514a-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6734-3p ; hsa-mir-6860 ; hsa-mir-6883-3p

Nearest miRNA

hsa-mir-10226/Upstream/1325707; hsa-mir-1250/Downstream/1575403;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/690693, chr17-CpG: 720/Downstream/26887

Upstream sequence

GCAGGATTGCCATGATCAACACCACTGTGCAAGTGGCTCCCAGAAGGACACTTTCCTCCTTTGGGGGTGTCCCCACGTCTTCCAGCAGCGCTCAGGCACT

Downstream sequence

GAGTCCTCAGGTTGTACCTCTTCAGACACGCTGGAGACTTAGAGATTGGCAAGTCTCAGTAGGGCCTGCCAACCTGAGCGGAGTAAGCATGAAGCAGGCT