Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008813
Fusion event
HBV-SLC13A5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
149
Orient
-
Integrated sequence
TGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGC| |GCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGT
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
Start
End
6610089/6706770 (Hg38)
Orient
+
Location type
Exonic
Target gene
Nearest miRNA
hsa-mir-1253/Upstream/51261; hsa-mir-10226/Downstream/310845;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/49286, chr17-CpG: 92/Downstream/6333
Upstream sequence
CGTGCGCAGGGCGATCCTCTTGTGCAGGTTCCAGCGCTCCACAGCCACGGCCACGATGAGGCCGCCCAGGAACAGCATGTTGGTGTCCTTCATGTACTGG
Downstream sequence
ACACACACCTGGAGCGTGGCACGAAGGCCTCATCAGGACTGTCCCTTGCCACACACTAGAGCCACCCAGTCCCCAGATGCTGACTTCAGGGACAGCTTGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.