VISDB Viral Integration Site DataBase

VIS ID

TVIS10008815

Fusion event

HBV-chr17 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1848

Orient

+

Integrated sequence

AGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCT| |TGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTAC

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7146225/7242906 (Hg38)

Orient

+

Location type

upstream;downstream

Target gene

CTDNEP1 ; GABARAP

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-26b-5p ; hsa-mir-1229-3p ; hsa-mir-1226-3p ; hsa-mir-4294 ; hsa-mir-3618 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-139-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-4494 ; hsa-mir-2392 ; hsa-mir-6165 ; hsa-mir-4499 ; hsa-mir-888-3p ; hsa-mir-3120-3p ; hsa-mir-4484 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-4651 ; hsa-mir-608 ; hsa-mir-486-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5194 ; hsa-mir-6738-5p ; hsa-mir-1914-3p ; hsa-mir-4725-5p ; hsa-mir-6752-3p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-4692 ; hsa-mir-1910-5p ; hsa-mir-4514 ; hsa-mir-6782-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6784-3p ; hsa-mir-6730-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-510-5p ; hsa-mir-887-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6825-5p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-744-5p ; hsa-mir-3195 ; hsa-mir-6087 ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-4644 ; hsa-mir-5011-3p ; hsa-mir-299-5p ; hsa-mir-5700 ; hsa-mir-3148 ; hsa-mir-4311 ; hsa-mir-651-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-122-5p ; hsa-mir-1321 ; hsa-mir-27b-5p ; hsa-mir-3140-5p ; hsa-mir-3689d ; hsa-mir-371a-3p ; hsa-mir-4427 ; hsa-mir-4475 ; hsa-mir-4694-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-6134 ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6892-5p ; hsa-mir-8055

Nearest miRNA

hsa-mir-1253/Upstream/19527; hsa-mir-10226/Downstream/845150;

Nearest TSS

Nearest CpG islands

chr17-CpG: 91/Target, None/Upstream, None/Downstream

Nearest cancer related gene

GABARAP(TSG, No orient, 0)

Upstream sequence

TTCACGAACCGTGTTGCTACGCTGAAGGCGGCCGTTGACACCAAAACAAAGTAGTACCCAAGTGGCGGAGATGATCTCCAGAAATAAGAAGTCAAAAAGA

Downstream sequence

AAACAGATGTTTGGAGAGATCTACAGAACGCTTAAGTGCCAAAATGAGTAGACCAATAGGGACTGGAGAGGAGGTTGGAAAGGTAGGGACTACGCCAGCG