VISDB Viral Integration Site DataBase

VIS ID

TVIS10008816

Fusion event

HBV-ACOX1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1932

Orient

+

Integrated sequence

CTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGA| |GCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGT

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

73940758/75944677 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-92b-5p ; hsa-mir-615-3p ; hsa-mir-3122 ; hsa-mir-3913-5p ; hsa-mir-155-5p ; hsa-mir-153-5p ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-1273e ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-1247-3p ; hsa-mir-3919 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3123 ; hsa-mir-302f ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-450a-1-3p ; hsa-mir-6796-5p ; hsa-mir-7109-5p ; hsa-mir-7977 ; hsa-mir-6742-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-3151-5p ; hsa-mir-491-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-383-3p ; hsa-mir-595 ; hsa-mir-7855-5p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-6788-3p ; hsa-mir-6499-3p ; hsa-mir-4474-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6787-3p ; hsa-mir-342-3p ; hsa-mir-3065-3p ; hsa-mir-1228-3p ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-619-5p ; hsa-mir-5004-3p ; hsa-mir-4665-3p ; hsa-mir-636 ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1293 ; hsa-mir-3165 ; hsa-mir-339-5p ; hsa-mir-363-5p ; hsa-mir-4421 ; hsa-mir-4483 ; hsa-mir-5699-3p ; hsa-mir-6134 ; hsa-mir-6745 ; hsa-mir-6748-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6771-3p

Nearest miRNA

hsa-mir-10226/Upstream/160070; hsa-mir-1250/Downstream/153342;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/3341, chr17-CpG: 67/Downstream/34213

Upstream sequence

CTAAATTTCTTCATAATTTAAACCTATGTTTAGTTGTGTGGCATATTTTTTCTCTCTTAATAGTACAAATCAGTGACGTTTACTCTATCTTTATTCTTGA

Downstream sequence

TTATATTGAATAAAGTTCAAGACAGAACATTCCAATATTAATAAAAATAGCATCAAATGTCAGATTTAGAttttttttttgagacggagtctcgctcagc