FSCN2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008820
Fusion event
HBV-FSCN2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
830
Orient
-
Integrated sequence
TTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATA| |CATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATAC
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79494300/81527274 (Hg38)
End
79494300/81527274 (Hg38)
Orient
+
Location type
Intronic
Target gene
FSCN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-10226/Upstream/76086; hsa-mir-4525/Downstream/166483;
Nearest TSS
ENST00000595228/Upstream/3427; ENST00000527221/Downstream/1122;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7387, chr17-CpG: 109/Downstream/705
Nearby gene
ACTG1(-14408) ; FSCN2(+1117) ;
Upstream sequence
CCCTTGCTTTTGGCTAGACTCCTGCCCTACGGGGACCCCCATGATGGCCACTCAGGAGATGGGCCCAGGAGGACAGGGGAGTGACTCCAGGCCATGACCG
Downstream sequence
GAAGGGGCCTGTGGCCCCTGTTCCCAGTCCCCAGGGAGACGGGAGGGTCACACGCTGTTATGAGGAAGAGGACACCGGGCTGGCCCTGGCCCAGGGTGGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate