Basic Information
VIS ID
TVIS10008827
Fusion event
HBV-LINC01924 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1827
Orient
-
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
62005709/64338474 (Hg38)
End
62005709/64338474 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01924
Nearest miRNA
hsa-mir-1-2/Upstream/5887316; hsa-mir-5011/Downstream/2743110;
Nearest TSS
ENST00000575820/Upstream/78419; ENST00000578545/Downstream/787236;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/335453, chr18-CpG: 88/Downstream/1412126
Upstream sequence
CAGAGGTGCTTGCCACCACTGTCTATGTTGGATccccagtagctactccaaagaaacatgcagaataaatacacactgtgcttggtaagcaaatatagct
Downstream sequence
ctaagtcaagtctccaaactcattgttccaaccacatggaaccctgctgtaaagacattctgaggtagtcactgGTGTGGACATAAAGGCTAGATTAAAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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