Basic Information
VIS ID
TVIS10008833
Fusion event
HBV-chr18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
429
Orient
-
Integrated sequence
CAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTC| |ATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCA
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
78016280/80258397 (Hg38)
End
78016280/80258397 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/7405015;
Nearest TSS
ENST00000575820/Upstream/10851;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/10609, None/Downstream
Nearby gene
PARD6G(-10883) ;
Upstream sequence
taggtgagggtgagggtgagggtgagggtgagggtgagggtgagggttagggttagggtgagggtgagggtgagggtgagggtgagggtgagggtgaggg
Downstream sequence
ttagggtgttagagggttagggttagggttagggttagggttagggggttagggggttagggggttagggggttagggtgagggtgagggtgagggtgag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate