hsa-mir-130b-3p _LIHC.png
ZNF567 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008837
Fusion event
HBV-ZNF567 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
3162
Orient
+
Integrated sequence
GGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTC| |ATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
37213281/36722379 (Hg38)
End
37213281/36722379 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF567
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-30b-5p ; hsa-mir-101-3p ; hsa-mir-19b-3p ; hsa-mir-652-3p ; hsa-mir-6884-3p ; hsa-mir-6826-5p ; hsa-mir-7151-5p ; hsa-mir-3120-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-5579-3p ; hsa-mir-103b ; hsa-mir-95-5p ; hsa-mir-32-3p ; hsa-mir-4282
Nearest miRNA
hsa-mir-10395/Upstream/1376752; hsa-let-7e/Downstream/2687244;
Nearest TSS
ENST00000633603/Upstream/9897; ENST00000591531/Downstream/50435;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/34692, chr19-CpG: 53/Downstream/50100
Nearby gene
ZNF567(-1056) ; ZNF850(+21099) ;
Upstream sequence
TAAAATTCAGTAGAAATTGAAATTTATTAATTAAtttattttttgaaatggagtctctatcgtccaggctggagtgcaatgacatggtctcaactcactg
Downstream sequence
taacctctgcctcctgggttcaaacgattctcctacctcagcctcccaagtagctggtactacaggcacgtgccaccacacgcagctaatttttgtattt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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