VISDB Viral Integration Site DataBase

VIS ID

TVIS10008838

Fusion event

HBV-ZFR2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2496

Orient

+

Integrated sequence

ACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTA| |TTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTA

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

3803777/3803779 (Hg38)

Orient

-

Location type

downstream

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-3665 ; hsa-mir-6886-5p ; hsa-mir-197-3p ; hsa-mir-4716-5p ; hsa-mir-1911-3p

Nearest miRNA

hsa-mir-1227/Upstream/1172986; hsa-let-7e/Downstream/157635;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/1958, chr19-CpG: 27/Downstream/2082

Upstream sequence

cctcggggagcctccagagcATCTCACTGTGTGTCTCTAGGATGGGGCCAGGGGAACCCTCAAGGACCGAGGCAGAGAGCTGGGTTATGGGAGGCGTTGA

Downstream sequence

GATGAATGATTCTCAGCCGGTGTGTCTGTGTTCCCAGGGGACCCTTGTGAGGGGACAGCCTGAGGATGCCCACACCTTGGGGAGCAGCCACTGAGCAGTG