Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008841
Fusion event
HBV-ACSBG2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
713
Orient
+
Integrated sequence
CATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCT| |TTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTC
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
Start
End
6151004/6150993 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1227/Upstream/1218253; hsa-let-7e/Downstream/238645;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/40126, chr19-CpG: 62/Downstream/48288
Upstream sequence
gcttgaggtcaggggttcgagaccagcctggccaacatggtgaaacgctgactctactaaaaaaacaaaaattagccaggcgtggtggcgcgtgtctgta
Downstream sequence
attccagctacttcggaggctgaggcaggagaatcgcttgaacccaggagacggaggttgcagtgagccgagatcgcactgctggactccagccttggca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.