SCN3A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008849
Fusion event
HBV-SCN3A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2179
Orient
+
Integrated sequence
CTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATA| |TGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGAT
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
End
166011561/165155051 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-128-1/Upstream/4747169; hsa-mir-10b/Downstream/3427892;
Upstream sequence
TGACAAGTAAGAGCACTGAACCTTTAAATCCTTTCAGTGGGATTCCATTTGCACTGCAGCTATTCTCCATACCATCTATAGATGACTTTTGCTCCCCTCC
Downstream sequence
CCTTCTAGTCTCAGTTAATAGCTAGAGCTTTAATTTGAAATTTTCACATCAACATCACTGATTTTTAAAATCTTTTAACGTGCTGTTTATATACCAACAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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