Fusion event
HBV-chr2 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
CTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTT| |TGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTA
End
216309909/215445186 (Hg38)
Nearest miRNA
hsa-mir-10b/Upstream/1687027; hsa-mir-1244-1/Downstream/2455327;
Upstream sequence
acctaaatgatctgcccgccttggcctccgaaagtgctgggattacaagtgtgagccactgcacctggccTCAACTTACATTACTTATTTTTCAAAAACT
Downstream sequence
AGAGAATCCATTAATTTTGGCTTGTTTGAATTTAAAAGTGATTATAATATTTTTGTTAGTTATATATGAGCAGTATTTCACTACAGCTCATCTTAAAGAT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.