VISDB Viral Integration Site DataBase

VIS ID

TVIS10008874

Fusion event

HBV-ASXL2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1776

Orient

-

Integrated sequence

CAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACT| |AGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCA

Chromosome

chr2

Cytoband

p23.3

Reference genome

Start

End

26094428/25871559 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-502-3p ; hsa-mir-326 ; hsa-mir-378a-5p ; hsa-mir-221-3p ; hsa-mir-4495 ; hsa-mir-544a ; hsa-mir-1-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-26b-3p ; hsa-mir-20a-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-767-5p ; hsa-mir-3663-3p ; hsa-mir-5002-5p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-6512-5p

Nearest miRNA

hsa-mir-1301/Upstream/542838; hsa-mir-10b/Downstream/2124808;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/197572, chr2-CpG: 108/Downstream/6085

Upstream sequence

AAATTTTTAATTTAAGTGTTCAAAAAAAAATCTGCTTTTTTCCCCTCCTTCAACAAACTAGGAGGCTTGTGGGCTTTCAGGATAGAGGAATAAAAACAGG

Downstream sequence

TCAGAAAAAATTATGAAATTAACACAAAAttttatttattttggtttttgagacagagtttcactcttgttgcccaggctggagtgcaatggcacgatct