VISDB Viral Integration Site DataBase

VIS ID

TVIS10008878

Fusion event

HBV-BIRC6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2896

Orient

+

Integrated sequence

ACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGA| |CCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCT

Chromosome

chr2

Cytoband

p22.3

Reference genome

Start

End

32612113/32387045 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-218-5p ; hsa-mir-615-3p ; hsa-mir-34a-5p ; hsa-let-7a-5p ; hsa-mir-342-3p

Nearest miRNA

hsa-mir-1301/Upstream/4390596; hsa-mir-10b/Downstream/145108;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/28848, chr2-CpG: 20/Downstream/240895

Upstream sequence

gtaactattacacaataaggatttacagacccatagaactctctgagacagctttgggctgaaactttattaatcgcttgaccatcctacgtgccctctt

Downstream sequence

tcttggaccacagtgatgttttaggtcagttcagtgccatgtttttgtaatgcctgaaagatcttttcccccatgcacagtcactgtagtgaatgcccat