Basic Information
VIS ID
TVIS10008879
Fusion event
HBV-SLC8A1-AS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1809
Orient
-
Integrated sequence
TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA
Host Sequence
Chromosome
chr2
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
40247407/40020267 (Hg38)
End
40247407/40020267 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
SLC8A1-AS1
Nearest miRNA
hsa-mir-1301/Upstream/4548781; hsa-mir-10b/Downstream/7357408;
Nearest TSS
ENST00000437798/Upstream/100574; ENST00000439606/Downstream/22083;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/240944, chr2-CpG: 16/Downstream/431070
Upstream sequence
ATtgatatagtttggctgtgtccccacccaaatctcatcttgaattgtagctcccacaattcccgtgtgtcatgggagggacccagtgggaggtaattga
Downstream sequence
atcacgggggtgggtctttaccatgctattcttgcaatagtgaataagtctcatgagcgctaatggttttataaagaggagttcccctgcacaagctctc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate