Basic Information
VIS ID
TVIS10008880
Fusion event
HBV-SLC8A1-AS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2624
Orient
+
Integrated sequence
CATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAA| |GATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAA
Host Sequence
Chromosome
chr2
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
40274033/40046893 (Hg38)
End
40274033/40046893 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
SLC8A1-AS1
Nearest miRNA
hsa-mir-1301/Upstream/4575407; hsa-mir-10b/Downstream/7330782;
Nearest TSS
ENST00000437798/Upstream/4543; ENST00000610721/Downstream/18432;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/267570, chr2-CpG: 16/Downstream/404444
Upstream sequence
ctccttcagccacttgattatccctcactgggcaaccttcaattcctctctcacttccaggccttcagtcatgctctttcctacaaagctcttcactaga
Downstream sequence
ttcttgtgctttgctaactcttgtttattcttcatctttcataccagctattcctccttcagacatgcctaatctgagctccacgttgcttttcccatta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate