VISDB Viral Integration Site DataBase

VIS ID

TVIS10008887

Fusion event

HBV-DDX27 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1812

Orient

-

Integrated sequence

AAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGC| |ACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCG

Chromosome

chr20

Cytoband

q13.13

Reference genome

Start

End

47853680/49237143 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-23b-3p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/2070085; hsa-mir-1-1/Downstream/626716;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/17613, chr20-CpG: 72/Downstream/40878

Upstream sequence

catatttaGCctgagcatggtagctcttgcctataacccagcactttgggaggccaaggcaggaggattgctagaggccaggagttcaagaccaacctga

Downstream sequence

gcaatatagtgagctgcctgtctctaaaaaaaaaaaattagctgggcatggtggtgtgtgcctgtagtcccagctattcagaaggctgaggcaggagatc