VISDB Viral Integration Site DataBase

VIS ID

TVIS10008907

Fusion event

HBV-PCOLCE2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1842

Orient

+

Integrated sequence

TGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATC| |ATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGG

Chromosome

chr3

Cytoband

q23

Reference genome

Start

End

142569878/142851036 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-182-5p

Nearest miRNA

hsa-let-7g/Upstream/8413130; hsa-mir-1224/Downstream/8714840;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/125900, chr3-CpG: 103/Downstream/37317

Upstream sequence

taggactactcagagaaagccaaatatgcagccctaattaatcatatagaataccctgcttctcattagtttgcctacagtttgcgcatgccaacagcct

Downstream sequence

acagaagggaagacagatgtaggtaggtcagtaaatgaggtggtgaaagcatatatagaattttttttctggattgcttttcttagtaaaatagaaaaca