VISDB Viral Integration Site DataBase

VIS ID

TVIS10008911

Fusion event

HBV-ANKRD28 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

235

Orient

-

Integrated sequence

ATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCA| |CAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCA

Chromosome

chr3

Cytoband

p25.1

Reference genome

Start

End

15782112/15740605 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-21-5p ; hsa-mir-221-3p ; hsa-mir-130b-5p ; hsa-mir-3180-5p ; hsa-mir-513b-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6885-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3617-3p ; hsa-mir-3074-3p ; hsa-mir-3614-3p

Nearest miRNA

hsa-mir-12127/Upstream/43234; hsa-let-7g/Downstream/133166;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/138531, chr3-CpG: 142/Downstream/118385

Upstream sequence

acATAATTTTCATTTGGATTTAGCCCAAAACTGAGTGAATTTGAATCATCCACTATAGGACCAAAGTATCTATATTTTTATAAACTTCAAATGTAATTTT

Downstream sequence

CAAACACAGAATACTAGAGATGTCAGCCTTGCCTTATCCACTCCCATTTTGGAATTCATAACACAAACATTAAAGCTTCTGGAAAGTTTGGGAAATACTT