Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008917
Fusion event
HBV-ULK4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1554
Orient
+
Integrated sequence
GACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGT| |CTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTA
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
Start
End
41767866/41726374 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/2588108; hsa-let-7g/Downstream/2387838;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/526234, chr3-CpG: 17/Downstream/164743
Upstream sequence
attatttgattaataCCCCCCAACTAGACTCAAGGGTTCATATGCCCATGTTGAAAAAATAAATAAATAGAGTTTACTTTAGACATTCCCCTATAATATT
Downstream sequence
ATAAACTGACTTTACTGACAAGAGAACATTATTTTCTAAAAGAATTCACATCTATAAAGGAGACAAAATGTGGAAACATTTGAGCATAGTGTCCCACAAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.