VISDB Viral Integration Site DataBase

VIS ID

TVIS10008922

Fusion event

HBV-CADM2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1541

Orient

-

Integrated sequence

GCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTAC| |GCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATT

Chromosome

chr3

Cytoband

p12.1

Reference genome

Start

End

85485801/85436651 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-624-3p ; hsa-mir-1277-5p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-410-3p ; hsa-mir-1273e ; hsa-mir-943 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4766-5p ; hsa-mir-6074 ; hsa-mir-4778-5p ; hsa-mir-512-3p ; hsa-mir-888-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-106b-5p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520e ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302e ; hsa-mir-520d-3p ; hsa-mir-302a-3p ; hsa-mir-302d-3p ; hsa-mir-5704 ; hsa-mir-4529-5p ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-3913-3p ; hsa-mir-6719-3p ; hsa-mir-489-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-203a-3p ; hsa-mir-627-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-195-3p

Nearest miRNA

hsa-let-7g/Upstream/50859; hsa-mir-12124/Downstream/1789538;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/476965, chr3-CpG: 78/Downstream/1553809

Nearest cancer related gene

CADM2(TSG, No orient, 0)

Upstream sequence

gagacagatgccttcctcttgtctcaactgcaagaggcattccttcctcttttactaatcctcctcagcacagaccctttacgggtgtcaggctggggga

Downstream sequence

TGAAAGCAGAAATTCTATAAATCAAACAttttaaagtaaacttttttattttagcaattttaagtttatagcaaaaataagcagaaagtgctaagatttc