Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008934
Fusion event
HBV-KCNIP4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1819
Orient
-
Integrated sequence
TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
Start
End
21517507/21515884 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/51126; hsa-mir-12115/Downstream/999428;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/815171, chr4-CpG: 95/Downstream/432578
Upstream sequence
gtgagcctcatatgatcagttgaaggcctgaatagaacaaaagtccaacctaccctgggcaagatgaaattctgctggcagacagctttcagacttgaac
Downstream sequence
catgagacaaataaatttctgttccttatacattacccagtctgtggtattctattatagtagcacaaaattggctaagagaatgaggtctgtctcttgt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.