VISDB Viral Integration Site DataBase

VIS ID

TVIS10008946

Fusion event

HBV-SRP72 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2118

Orient

+

Integrated sequence

GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG| |GGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTT

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

57356070/56489904 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1229-3p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5580-3p ; hsa-mir-6083 ; hsa-mir-6516-3p ; hsa-mir-205-3p

Nearest miRNA

hsa-mir-12113/Upstream/3777157; hsa-mir-1243/Downstream/4432715;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/21875, chr4-CpG: 48/Downstream/15512

Upstream sequence

GAGGTCAGCACTTCCCTCCAGTTTTGGTGTGAGGAAATGATACAGGATCCGATTTATTTGATCTTAGTAACTTTCTTCTTAGATCCATCTTCATCCATTG

Downstream sequence

CTGCATGGGCAGTATCCAACTTAAAATTATACATACGCTGTGCAGGTGGCATTTATACTGTTAGTACTGTTAGCAGTGGAGGGGTATCAGTGCTCTGGGA