Fusion event
HBV-FBXL17 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
GTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCT| |CACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACC
End
107313993/107978292 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/7161727; hsa-mir-103a-1/Downstream/2535537;
Upstream sequence
ttaggttcacagcaaattttagtggaaggtacagagatttcccatagtctccctgccccacacatgcacagccttcctcatcgtcaacatctcccaccag
Downstream sequence
tgaagcagggatgataacaatccctccctaaaactgctcccactccttgtttgggggctgaaactgcctttgtaaaactaatgaaaggccacaaggttag
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.