FBXL17 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008951
Fusion event
HBV-FBXL17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2052
Orient
+
Integrated sequence
GTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCT| |CACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACC
Host Sequence
Chromosome
chr5
Cytoband
q21.3
Reference genome
End
107313993/107978292 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/7161727; hsa-mir-103a-1/Downstream/2535537;
Upstream sequence
ttaggttcacagcaaattttagtggaaggtacagagatttcccatagtctccctgccccacacatgcacagccttcctcatcgtcaacatctcccaccag
Downstream sequence
tgaagcagggatgataacaatccctccctaaaactgctcccactccttgtttgggggctgaaactgcctttgtaaaactaatgaaaggccacaaggttag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate