VISDB Viral Integration Site DataBase

VIS ID

TVIS10008957

Fusion event

HBV-HSPA9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2249

Orient

+

Integrated sequence

ACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTAT| |AGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTT

Chromosome

chr5

Cytoband

q31.2

Reference genome

Start

End

137896254/138560565 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1226-3p ; hsa-mir-615-3p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-302b-5p ; hsa-mir-302d-5p

Nearest miRNA

hsa-mir-10397/Upstream/912916; hsa-mir-103a-1/Downstream/2003106;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/16829, chr5-CpG: 67/Downstream/14679

Upstream sequence

tcattgatctataagtctatccttgtgccagtgccacactgtattaattactgtagctgagtagtaaattttgaaataaaaaagtgtgagtcttccaact

Downstream sequence

tttttttttttttgagacggagtctcgctgtgtcgctcaggctggagtgcggtggcgcaatctccactcaccgcaagctccacctcctgcgttcacgcca