VISDB Viral Integration Site DataBase

VIS ID

TVIS10008958

Fusion event

HBV-UGT3A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2125

Orient

+

Integrated sequence

TTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTA| |ATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCT

Chromosome

chr5

Cytoband

p13.2

Reference genome

Start

End

35993485/35993383 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-181a-5p ; hsa-mir-498 ; hsa-mir-513b-5p ; hsa-mir-219a-2-3p ; hsa-mir-219b-3p ; hsa-mir-3156-5p ; hsa-mir-6715b-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-4272 ; hsa-mir-4802-3p ; hsa-mir-4680-3p

Nearest miRNA

hsa-mir-10397/Upstream/3598908; hsa-mir-103a-1/Downstream/154509;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/375146, chr5-CpG: 85/Downstream/158012

Upstream sequence

ttcgtcaatttctcctttgaaaaccttggggcaaaatataatttgaaattcggttattttttagatgttaggagataccagtcaggtattataaatgtta

Downstream sequence

aacccaggaggcggaggttgcagtgagccaagatcgcgccactgcactcaagcctggtgacagagcgagactccgtctcaaaaaaaaaaaaatgcagatt