IQGAP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008962
Fusion event
HBV-IQGAP2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1765
Orient
-
Integrated sequence
TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
End
75891413/76595588 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/3716925; hsa-mir-103a-1/Downstream/6244567;
Nearest cancer related gene
IQGAP2(TSG, No orient, 0)
Upstream sequence
cttcacagggtggcaggaaagagaaatgccaagcaaaagggaaaaaggtcccttataaaaccatcagatctagtgagaactcactcactatcatgagaac
Downstream sequence
tctttacaaaaaaaatttaaaaattagccgggtgtggtggcacacaactgtagccccagatactgtagagactgaggtcggaggatctccagagcccagg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate