Basic Information
VIS ID
TVIS10008969
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
400
Orient
+
Integrated sequence
CTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCA| |TCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAAC
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
End
16774224/16773993 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/632369; hsa-mir-10398/Downstream/1797791;
Nearby gene
ATXN1(-12503) ;
Upstream sequence
TGTAGGCTGTATCCCCTCAGTGTGGGCTTGTCTCTCAGTAGGAACTTCTAATTGAGTGTTTTGTGCATTTGACTGAAAGAGTCTCATTCCACTTTCAATA
Downstream sequence
AAAAGCACATTCAGTTGACTCCACATCTGAGAAGTGACCAGTGATTGGTACCAGGAATGAGTTAGGTTCCCAACCCCAACACCATCTCTCAGTGCATCTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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