Basic Information
VIS ID
TVIS10008980
Fusion event
HBV-LOC100506207 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2631
Orient
+
Integrated sequence
AAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCA| |ATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTAC
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
8638328/8638095 (Hg38)
End
8638328/8638095 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LOC100506207
Nearest miRNA
hsa-mir-3691/Upstream/2468660; hsa-mir-10398/Downstream/1801622;
Nearest TSS
ENST00000381078/Upstream/202484; ENST00000645232/Downstream/523682;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/202187, chr6-CpG: 41/Downstream/760765
Upstream sequence
GATTCATTGGGGGAATGGCATGGGTCACAGCACATAGCTTCTCCGTCTTCCAGTTCACTGCATCTCCACCCCGATCTCATGACTATCTATGATTAAGTCA
Downstream sequence
TAATTAAGTAATGTGGCCCAGAGGAGTTAATCATTTAAAACCCTGTCATCTTTCTCAAGTTTGCAGATAGAAGAGCTAGCACAGAAGGCACCTGCCAGGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate